Biomarkers: Validation & Verification

Biomarker research is a continuous process beginning with discovery & then proceeds to validation process till the implementation of biomarkers in the clinical setting.  Candidate biomarkers which are identified in discovery stage need to be validated across the number of samples. The challenge is to develop a fast and targeted analysis method that is capable of analyzing as many identified candidates as possible in minimum hundred and potentially even thousands of samples. Biomarker candidates identified during discovery process are validated using larger samples which covers a broad section of patients. The verification stage provides confirmation that a particular methodology is suitable to be used in the validation phase.