Biomarkers in Drug Discovery & Development
The aim of drug discovery and development is to identify effective drug and provide it in right dosage at right frequency to affected organism. Biomarkers are effective tool to identify the mechanism of action of the drug that can correlate pharmacokinetics and pharmacodynamics (PK & PD) of drug. Biomarkers aids in finding the safe procedure of drug administration. In genomics, the biomarker challenge identifies unique molecular signatures in complex biological mixtures which unambiguously correlate to biological events for validating novel drug targets and also predict drug response.